Mianserin

Overview

Mianserin (Mianserine) is an orally active H1 receptor antagonist. Mianserin can activate κ-opioid receptor and octopamine receptor. Mianserin increases ERK1/2 and CREB phosphorylation, and antagonizes full κ-opioid agonist and Dynorphin A ( HY-P1333 )-induced MAPK phosphorylation. Mianserin modulates social and exploratory behaviour, raises electroconvulsive thresholds. Mianserin can be used for the research of neurological disease , such as depression and epilepsy.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Depression | Products > Disease Areas > Epilepsy | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > Histamine Receptor | Products > Signaling Pathways > Opioid Receptor | Products > Signaling Pathways > ERK

Product Information

• Catalog No.: HY-B0188
• CAS No.: 24219-97-4
• Molecular Formula: C18H20N2
• Molecular Weight: 264.36
• Purity: 99.42%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1 mg/mL (3.78 mM); Clear solution
• Availability: In-stock

Source

Original product source