Naratriptan-d 3 hydrochloride

Overview

Naratriptan-d 3 (GR-85548A-d 3 ) is the deuterium labeled Naratriptan hydrochloride ( HY-B0197A ). Naratriptan hydrochloride is a selective 5-HT1B/1D receptor agonist. Naratriptan hydrochloride is peripherally active and has good oral bioavailability, inducing cranial artery vasoconstriction by activating 5-HT1B/1D receptors (EC 50 =0.11 μM for dog basilar artery). Naratriptan hydrochloride also inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation and reduces sterile inflammation. Naratriptan hydrochloride is mainly used in the research of acute migraine, targeting cranial vascular and neuroinflammatory mechanisms.

Application

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Product Information

• Catalog No.: HY-B0197AS
• CAS No.: 1190021-64-7
• Molecular Formula: C17H23D3ClN3O2S
• Molecular Weight: 374.94
• Purity: 99.98%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source