Naratriptan-d 3

Overview

Naratriptan -d 3 (GR-85548A-d 3 ) is the deuterium labeled Naratriptan ( HY-B0197 ). Naratriptan is a selective 5-HT1B/1D receptor agonist. Naratriptan is peripherally active and has good oral bioavailability, inducing cranial artery vasoconstriction by activating 5-HT1B/1D receptors (EC 50 =0.11 μM for dog basilar artery). Naratriptan also inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation and reduces sterile inflammation. Naratriptan is mainly used in the research of acute migraine, targeting cranial vascular and neuroinflammatory mechanisms.

Application

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Product Information

• Catalog No.: HY-B0197S
• CAS No.: 1190043-69-6
• Molecular Formula: C17H22D3N3O2S
• Molecular Weight: 338.48
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source