(E/Z)-Afatinib (Standard)

Overview

(E/Z)-Afatinib (Standard) is the analytical standard of (E/Z)-Afatinib. This product is intended for research and analytical applications. (E/Z)-Afatinib ((E/Z)-BIBW 2992) is the mixture of (E)-Afatinib and (Z)-Afatinib. Afatinib ( HY-10261 ) is an irreversible inhibitor of EGFR , by irreversibly binding to their ATP binding site to block activation of EGFR , HER2, HER4, and EGFRvIII. Afatinib used in co-administration with Temozolomide ( HY-17364 ), potently targeting to EGFRvIII-cMet signaling in glioblastoma cells.

Application

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Product Information

• Catalog No.: HY-10261BR
• CAS No.: 439081-18-2
• Molecular Formula: C24H25ClFN5O3
• Molecular Weight: 485.94
• Purity: 98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source