Disulfiram

Overview

Disulfiram (Tetraethylthiuram disulfide) is a specific inhibitor of aldehyde-dehydrogenase ( ALDH1 ) , used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells. Disulfiram, a copper ion carrier, with Cu 2+ increases intracellular ROS levels and induces cuproptosis .

Application

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Product Information

• Catalog No.: HY-B0240
• CAS No.: 97-77-8
• Molecular Formula: C10H20N2S4
• Molecular Weight: 296.54
• Purity: 99.77%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 1 year , -20°C, 6 months
• Solubility: ≥ 2.08 mg/mL (7.01 mM); Clear solution
• Availability: In-stock

Source

Original product source