Adefovir dipivoxil

Overview

Adefovir dipivoxil is an orally active adenosine analog and Adefovir prodrug. Adefovir dipivoxil inhibits DNA synthesis , activates the ATR signaling pathway, and disrupts the KCTD12-CDK1 interaction. Adefovir dipivoxil has antiviral activity against PRV , HBV , and orthopoxviruses . Adefovir dipivoxil has inhibitory effects on both lamivudine-resistant and wild-type strains . Adefovir dipivoxil has antitumor activity against lung and colon cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Viral Infection | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Disease Areas > Pancreatic Cancer | Products > Disease Areas > Orthopoxvirus Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Infection | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > CDK | Products > Signaling Pathways > HBV | Products > Signaling Pathways > Orthopoxvirus | Products > Signaling Pathways > HSV | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > ATM/ATR

Product Information

• Catalog No.: HY-B0255
• CAS No.: 142340-99-6
• Molecular Formula: C20H32N5O8P
• Molecular Weight: 501.47
• Purity: 99.03%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (4.99 mM); Clear solution
• Availability: In-stock

Source

Original product source