Prothionamide

Overview

Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of OCT1 with a K m value of 805.8 μM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA . Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 µg/mL) and Mycobacterium leprae . Prothionamide is used in the research of tuberculosis and leprosy.

Application

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Product Information

• Catalog No.: HY-B0306
• CAS No.: 14222-60-7
• Molecular Formula: C9H12N2S
• Molecular Weight: 180.28
• Purity: 99.87%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (13.87 mM); Clear solution
• Availability: In-stock

Source

Original product source