Idoxuridine

Overview

Idoxuridine (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases . Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC 50 value of 4.3 μM. Idoxuridine shows anti-orthopoxvirus activity.

Application

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Product Information

• Catalog No.: HY-B0307
• CAS No.: 54-42-2
• Molecular Formula: C9H11IN2O5
• Molecular Weight: 354.10
• Purity: 99.81%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (5.87 mM); Clear solution
• Availability: In-stock

Source

Original product source