Sulfamethizole is a sulfathiazole antibiotic . Sulfamethizole inhibits the synthesis of folic acid and thymine, and selectively suppresses Photobacterium phosphoreum bioluminescence. Sulfamethizole exerts antibacterial activity against Escherichia coli -mediated urinary tract infections but no activity against sulII gene-positive Escherichia coli . Sulfamethizole is applicable for the research of urinary tract infections and Photobacterium phosphoreum bioluminescence mechanisms.
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