Linaclotide

Overview

Linaclotide is a peptide agonist of guanylate cyclase 2C that is undergoing clinical trials for use in treating abdominal pain in patients with irritable bowel syndrome (IBS) accompanied by constipation. The drug also has promising outlooks for the treatment of gastroparesis, ulcerative colitis, chronic intestinal pseudo-obstruction (CIPO), and inertia coli as well. Sequence: CCEYCCNPACTGCY (Disulfide bridge: Cys1-Cys6, Cys2-Cys10, Cys5-Cys13) Source summary: Linaclotide is a peptide used in the treatment of irritable bowel syndrome and chronic constipation, offering therapeutic benefits.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Inflammation / Immunology | Guanylate Cyclase

Product Information

• Catalog No.: B0084-152760
• CAS No.: 851199-59-2
• Molecular Formula: C59H79N15O21S6
• Molecular Weight: 1526.74
• Purity: ≥95%
• Storage: Store at -20°C
• Solubility: Soluble in DMSO (Slightly, Heated), Methanol (Slightly, Heated), Water (Slightly, Heated)

Source

Original product source