Fenbendazole

Overview

Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent and acts on helminthes primarily by binding to tubulin and disrupting the tubulin microtubule equilibrium. Fenbendazole stabilizes the transcriptional activator HIF-1α . Fenbendazole possesses an efficient anti-proliferative activity and induces apoptosis . Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53.

Application

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Product Information

• Catalog No.: HY-B0413
• CAS No.: 43210-67-9
• Molecular Formula: C15H13N3O2S
• Molecular Weight: 299.35
• Purity: 99.94%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 1 mg/mL (3.34 mM); Clear solution
• Availability: In-stock

Source

Original product source