Niflumic acid (Standard)

Overview

Niflumic acid (Standard) is the analytical standard of Niflumic acid. This product is intended for research and analytical applications. Niflumic acid is a calcium-activated chloride channel blocker and COX -2 inhibitor with the IC 50 value of 100 nM. Niflumic acid induces apoptosis through caspase-8 / Bid / Bax pathway in lung cancer cells. Niflumic acide exhibits anti-tumor activity by affecting the expression of ERK1/2 and the activity of MMP2 and MMP9 . Niflumic acid has orally bioactivity. Niflumic acid acts on rheumatoid arthritis.

Application

Products | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Chloride Channel | Products > Signaling Pathways > COX

Product Information

• Catalog No.: HY-B0493R
• CAS No.: 4394-00-7
• Molecular Formula: C13H9F3N2O2
• Molecular Weight: 282.22
• Purity: 99.93%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source