Sulfamerazine

Overview

Sulfamerazine (RP2632) is a brain-penetrant and orally active sulfonamide antibiotic and α-synuclein inhibitor with human α-synuclein K D of 352 μM. Sulfamerazine inhibits the synthesis of dihydrofolate by bacteria , thereby inhibiting bacterial growth. Sulfamerazine inhibits α-synuclein fibrillation, reduces α-synuclein aggregation-associated toxicity and α-synuclein aggregate accumulation. Sulfamerazine can be used for the research of Parkinson’s disease and bacterial infection .

Application

Products | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Parkinson's Disease | Products > Disease Areas > Infection | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Research Areas > Infection | Products > Signaling Pathways > Antibiotic | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > α-synuclein

Product Information

• Catalog No.: HY-B0512
• CAS No.: 127-79-7
• Molecular Formula: C11H12N4O2S
• Molecular Weight: 264.30
• Purity: 99.82%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (9.46 mM); Clear solution
• Availability: In-stock

Source

Original product source