Triflusal

Overview

Triflusal is an orally bioavailable, blood-brain barrier-permeable dual Cyclooxygenase-1 ( COX-1 ) / cAMP phosphodiesterase inhibitor. Triflusal inhibits platelet aggregation, NF-κB activation, iNOS activity, and prostaglandin synthesis in ischaemic tissue. Triflusal stimulates neutrophil nitric oxide production, eNOS protein expression, and cNOS activity. Triflusal alleviates cerebral ischemic injury in rats and ameliorates pathological lesions and related gene expression in transgenic Alzheimer’s disease models. Triflusal can be used for the research of thromboembolic/ischemic cardiovascular and cerebrovascular diseases, and Alzheimer’s disease.

Application

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Product Information

• Catalog No.: HY-B0531
• CAS No.: 322-79-2
• Molecular Formula: C10H7F3O4
• Molecular Weight: 248.16
• Purity: 99.56%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 3 mg/mL (12.09 mM); Clear solution
• Availability: In-stock

Source

Original product source