Desloratadine

Overview

Desloratadine (Sch34117) is an orally active and selective H1 receptor antagonist ( K i =0.9 nM) with anti-inflammatory and anti-allergic activities. Desloratadine inhibits the release of histamine and LTC4 from human basophils and targets the regulatory signals of IL-4 and IL-13 production in basophils. Desloratadine significantly alleviates SAR symptoms in patients with concurrent asthma and can be used in the study of seasonal allergic rhinitis and chronic idiopathic urticaria.

Application

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Product Information

• Catalog No.: HY-B0539
• CAS No.: 100643-71-8
• Molecular Formula: C19H19ClN2
• Molecular Weight: 310.83
• Purity: 99.98%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 0.67 mg/mL (2.16 mM); Clear solution
• Availability: In-stock

Source

Original product source