Tetrabenazine (Standard)

Overview

Tetrabenazine (Standard) is the analytical standard of Tetrabenazine ( HY-B0590 ). This product is intended for research and analytical applications. Tetrabenazine (Ro 1-9569) is a brain-penetrant and orally active VMAT2 -selective ligand with human VMAT2 K i 100 nM. Tetrabenazine binds VMAT2 to block monoamine uptake into synaptic vesicles, potentiates cytoplasmic monoamine degradation. Tetrabenazine weakly blocks dopamine D2 receptors , and increases dopamine turnover via elevated cerebrospinal fluid homovanillic acid. Tetrabenazine can be used for the research of Huntington’s disease, tardive dyskinesia, and Tourette’s syndrome.

Application

Products | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Huntington's Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Monoamine Transporter | Products > Signaling Pathways > Dopamine Receptor

Product Information

• Catalog No.: HY-B0590R
• CAS No.: 58-46-8
• Molecular Formula: C19H27NO3
• Molecular Weight: 317.43
• Purity: 98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source