Tafluprost acid

Overview

Tafluprost acid (AFP-172), an active metabolic form of Tafluprost, is a selective prostanoid FP receptor agonist. Tafluprost acid shows a high affinity for human prostanoid FP receptor with K i and EC 50 values of 0.4 nM and 0.53 nM, respectively. Tafluprost acid has 126 times weaker binding affinity for prostanoid EP3 receptor ( IC 50 =67 nM) than for the prostanoid FP receptor. Tafluprost acid can be used in the research of glaucoma.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Endocrinology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Prostaglandin Receptor | Products > Signaling Pathways > Drug Metabolite

Product Information

• Catalog No.: HY-B0601
• CAS No.: 209860-88-8
• Molecular Formula: C22H28F2O5
• Molecular Weight: 410.45
• Purity: 99.88%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (6.09 mM); Clear solution
• Availability: In-stock

Source

Original product source