Epinastine

Overview

Epinastine (WAL801) is a selective and orally active histamine H1 receptor antagonist, CD96/PVR inhibitor and mast cell stabilizer. Epinastine has high affinity for neuronal octopamine receptors in locusts ( K i = 2 nM) and honeybees ( K i = 1.1 nM). Epinastine hydrochloride inhibits TARC , IL-8 , and IL-4 . Epinastine activates anti-colon cancer immunity and inhibits Substance P ( HY-P0201 )-induced scratching behavior and increased vascular permeability. Epinastine can be used in the research of allergic diseases.

Application

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Product Information

• Catalog No.: HY-B0640
• CAS No.: 80012-43-7
• Molecular Formula: C16H15N3
• Molecular Weight: 249.32
• Purity: 98.0%
• Storage: 4°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (10.03 mM); Clear solution
• Availability: In-stock

Source

Original product source