Epinastine (hydrochloride) (Standard) is the analytical standard of Epinastine hydrochloride ( HY-B0640A ). This product is intended for research and analytical applications. Epinastine hydrochloride (WAL801 hydrochloride) is a selective and orally active histamine H1 receptor antagonist, CD96/PVR inhibitor and mast cell stabilizer. Epinastine hydrochloride has high affinity for neuronal octopamine receptors in locusts ( K i = 2 nM) and honeybees ( K i = 1.1 nM). Epinastine hydrochloride inhibits TARC , IL-8 , and IL-4 . Epinastine hydrochloride activates anti-colon cancer immunity and inhibits Substance P ( HY-P0201 )-induced scratching behavior and increased vascular permeability. Epinastine hydrochloride can be used in the research of allergic diseases.
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