Pazufloxacin (mesylate) (Standard) is the analytical standard of Pazufloxacin mesylate ( HY-B0724A ). This product is intended for research and analytical applications. Pazufloxacin mesylate is an orally active fluoroquinolone antimicrobial agent. Pazufloxacin mesylate inhibits DNA gyrase with IC 50 values of 0.88 μg/mL ( E. coli ) and 1.9 μg/mL ( P. aeruginosa ). Pazufloxacin mesylate exhibits broad-spectrum antimicrobial activity, with MIC 90 values ranging from 0.025 to 100 μg/mL against Gram-positive and Gram-negative bacteria, non-fermenting bacteria, Legionella spp., and anaerobic bacteria. Pazufloxacin mesylate is indicated for research on systemic infections, lung infections, urinary tract infections, and Legionella pneumonia.
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