Fimasartan

Overview

Fimasartan (BRA-657) is an orally effective angiotensin receptor AT1 non-peptide antagonist. Fimasartan has antihypertensive effects. Fimasartan improves neuroinflammation and brain injury mediated by NLRP3 inflammatome after intracerebral hemorrhage, and has neuroprotective effect. Fimasartan inhibits the expression of inducible nitric oxide synthase through the inactivation of NF-κB and activator protein-1.

Application

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Product Information

• Catalog No.: HY-B0780
• CAS No.: 247257-48-3
• Molecular Formula: C27H31N7OS
• Molecular Weight: 501.65
• Purity: 99.60%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (4.98 mM); Clear solution
• Availability: In-stock

Source

Original product source