Treprostinil (UT-15C) diethanolamine is a potent EP2 , DP1 and IP agonist with K i values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP , EP1, EP4, EP3 and FP , respectively. Treprostinil (UT-15C) diethanolamine increases upregulation of cAMP toward maintaining homeostasis within the vasculature. Treprostinil (UT-15C) diethanolamine can result in vasodilatation of human pulmonary arteries.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Endocrinology | Products > Signaling Pathways > Prostaglandin Receptor
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