Dinotefuran

Overview

Dinotefuran is an orally active and competitive inhibitor and insecticide targeting insect nicotinic acetylcholine receptors ( nAChRs ). Dinotefuran blocks neural signaling and induces neural dysfunction in insects. Dinotefuran binds to [ 3 H]epibatidine in the neural cord membrane of American cockroach with an IC 50 of 890 nM and to [ 3 H]α-bungarotoxin with an IC 50 of 36.1 μM. Dinotefuran exhibits knockdown activity (KD 50 =0.351 nmol/g) and lethal activity (LD 50 =0.173 nmol/g) against German cockroach. Dinotefuran is mainly used for agricultural pest control, such as field control of piercing-sucking and chewing insects (e.g., aphids, planthoppers), while its environmental toxicological effects (e.g., oxidative stress and reproductive neurotoxicity on earthworms) are also a research focus to assess ecological risks.

Application

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Product Information

• Catalog No.: HY-B0827
• CAS No.: 165252-70-0
• Molecular Formula: C7H14N4O3
• Molecular Weight: 202.21
• Purity: 99.74%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 25 mg/mL (123.63 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source