Org37684 is a highly potent 5-HT 2C receptor agonist ( pEC 50 =8.17). Org37684 exhibits a rank order of potency of 5-HT 2C >5-HT 2B >5-HT 2A . Its selectivity for the 5-HT2C receptor is approximately 2.5 times over the 5-HT2B (pEC 50 =7.96) and ten times for the 5-HT 2A (pEC 50 =7.11) receptor.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > 5-HT Receptor
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