Suramin sodium salt

Overview

Suramin sodium salt (Suramin hexasodium salt) is a reversible and competitive protein-tyrosine phosphatases (PTPases) inhibitor. Suramin sodium salt is a potent inhibitor of sirtuins : SirT1 ( IC 50 =297 nM), SirT2 ( IC 50 =1.15 μM), and SirT5 ( IC 50 =22 μM). Suramin sodium salt is a competitive inhibitor of reverse transcriptase ( DNA topoisomerase II : IC 50 =5 μM). Suramin sodium salt is a potent SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitor. Suramin sodium salt efficiently inhibits IP5K and is an antiparasitic , anti-neoplastic and anti-angiogenic agent.

Application

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Product Information

• Catalog No.: HY-B0879A
• CAS No.: 129-46-4
• Molecular Formula: C51H34N6Na6O23S6
• Molecular Weight: 1429.17
• Purity: 99.98%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.08 mg/mL (1.46 mM); Clear solution
• Availability: In-stock

Source

Original product source