Acetohexamide

Overview

Acetohexamide is an orally active first-generation sulfonylurea agent used in research related to type 2 diabetes and cancer . Acetohexamide exerts reductase activity in human erythrocytes. Acetohexamide stimulates the pancreas to secrete insulin . Acetohexamide inhibits ATP-sensitive potassium channels in the β cells of the pancreas. Acetohexamide can inhibit the formation of circular chemorepellent induced defects (CCIDs) in lymphendothelial cell (LEC) monolayers. Acetohexamide inhibits markers of epithelial-to-mesenchymal-transition and migration. Acetohexamide suppresses the synthesis of 12(S)-HETE. Acetohexamide can potentiate hypoglycaemic action.

Application

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Product Information

• Catalog No.: HY-B0881
• CAS No.: 968-81-0
• Molecular Formula: C15H20N2O4S
• Molecular Weight: 324.40
• Purity: 99.67%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 2.5 mg/mL (7.71 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source