Edrophonium chloride is a short-acting acetylcholinesterase ( AChE ) inhibitor. Edrophonium chloride has K i values of 0.2, 0.2, and 0.4 μM and IC 50 values of 0.2, 0.05, and 0.5 μM for AChE in human erythrocytes, purified calf forebrain, and purified octopus brain, respectively. Edrophonium chloride can be used to detect early digitalis toxicity and in the study of myasthenia gravis.
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