Hydrastine (Standard)

Overview

Hydrastine (Standard) is the analytical standard of Hydrastine ( HY-B0927 ). This product is intended for research and analytical applications. Hydrastine ((-)-β-Hydrastine; (1R,9S)-β-Hydrastine) is a selective competitive inhibitor of tyrosine hydroxylase (TH) , inhibiting dopamine biosynthesis (IC 50 =20.7 μM, PC12 cells). Hydrastine also inhibits the organic cation transporter OCT1 ( IC 50 =6.6 μM). Hydrastine may cause neuronal toxicity through mitochondrial dysfunction rather than oxidative stress damage, and can aggravate cell apoptosis when combined with L-DOPA. Hydrastine can be used to study Parkinson's disease-related dopaminergic neuronal damage.

Application

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Product Information

• Catalog No.: HY-B0927R
• CAS No.: 118-08-1
• Molecular Formula: C21H21NO6
• Molecular Weight: 383.39
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source