Trimetazidine

Overview

Trimetazidine is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC 50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine triggers autophagy . Trimetazidine is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > Autophagy | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Autophagy

Product Information

• Catalog No.: HY-B0968A
• CAS No.: 5011-34-7
• Molecular Formula: C14H22N2O3
• Molecular Weight: 266.34
• Purity: 99.84%
• Storage: 4°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Solubility: ≥ 2.08 mg/mL (7.81 mM); Clear solution
• Availability: In-stock

Source

Original product source