NAS-181 dimesylate

Overview

NAS181 is a potent and selective antagonist of rat 5-HT 1B receptor, with a K i of 47 nM. NAS181 shows 13-fold selectivity for r5-HT 1B over bovine 5-HT 1B receptor (K i =630 nM). NAS181 increases the 5-HT turnover and the synaptic concentration of 5-HT by inhibiting terminal r5-HT 1B autoreceptors.

Application

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Product Information

• Catalog No.: HY-103156
• CAS No.: 1217474-40-2
• Molecular Formula: C21H34N2O10S2
• Molecular Weight: 538.63
• Purity: 96.37%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source