Lofexidine-d 4 hydrochloride

Overview

Lofexidine-d 4 hydrochloride (Baq-168-d 4 ) is the deuterium labeled Lofexidine hydrochloride ( HY-B1052 ). Lofexidine hydrochloride (Baq-168) is an orally active agonist of the imidazoline I1 receptor ( imidazoline I1 receptor ) ( Ki : 1.9 nM) and α 2 -adrenergic receptor ( α2-adrenergic receptor ). Lofexidine hydrochloride binds to the α 2 A-adrenergic receptor, reduces sympathetic outflow, lowers blood pressure, and exhibits vasoconstrictive effects. Lofexidine hydrochloride regulates the expression of c-fos and alleviates opioid withdrawal symptoms. Lofexidine hydrochloride is applicable to research on opioid addiction and withdrawal.

Application

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Product Information

• Catalog No.: HY-B1052S
• CAS No.: 1206845-57-9
• Molecular Formula: C11H9D4Cl3N2O
• Molecular Weight: 299.62
• Purity: 99.98%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source