Hycanthone

Overview

Hycanthone is a thioxanthenone DNA intercalator and inhibits RNA synthesis as well as the DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits apurinic endonuclease-1 (APE1) by direct protein binding with a K D of 10 nM. Hycanthone is a bioactive metabolite of Lucanthone ( HY-B2098 ) and has anti-schistosomal agent.

Application

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Product Information

• Catalog No.: HY-B1099
• CAS No.: 3105-97-3
• Molecular Formula: C20H24N2O2S
• Molecular Weight: 356.48
• Purity: 99.81%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 1.25 mg/mL (3.51 mM); Clear solution
• Availability: In-stock

Source

Original product source