Cefamandole sodium

Overview

Cefamandole (Cephamandole) sodium is a semi-synthetic second-generation cephalosporin antibiotic with broad-spectrum antimicrobial activity. Cefamandole sodium is resistant to hydrolysis by β-lactamases produced by some Gram-negative bacteria. Cefamandole sodium kills Gram-positive cocci and various Gram-negative bacilli mainly by inhibiting cell wall synthesis, but it is inactive against Pseudomonas , Proteus vulgaris and Providencia stuartii , and its efficacy is affected by inoculum size. The plasma elimination half-life of Cefamandole sodium in rats is only 0.4 h, it is mainly excreted in urine in biologically active form, and it hardly penetrates the non-inflamed blood-brain barrier. Cefamandole sodium is widely used in studies related to bacterial infections.

Application

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Product Information

• Catalog No.: HY-B1128A
• CAS No.: 30034-03-8
• Molecular Formula: C18H17N6NaO5S2
• Molecular Weight: 484.48
• Purity: 95.0%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: 100 mg/mL (206.41 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source