Crotamiton

Overview

Crotamiton is a TRPV4 inhibitor. Crotamiton inhibits TRPV4 currents. Crotamiton inhibits TRPV4 selective agonist-induced pruritus-related behaviors in mice. Crotamiton inhibits Histamine- and Chloroquine-induced calcium influx via the H1R / TRPV1, MRGPRA3/TRPA1 pathways, and also suppresses calcium influx in primary mouse dorsal root ganglion neurons. Crotamiton is applicable to research related to pruritus, scabies, and non-scabietic pruritus.

Application

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Product Information

• Catalog No.: HY-B1177
• CAS No.: 483-63-6
• Molecular Formula: C13H17NO
• Molecular Weight: 203.28
• Purity: 98.07%
• Storage: Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 3.5 mg/mL (17.22 mM); Clear solution
• Availability: In-stock

Source

Original product source