Terfenadine-d 3

Overview

Terfenadine-d 3 ((±)-Terfenadine-d 3 ) is the deuterium labeled Terfenadine. Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC 50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist , acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis , simultaneously activates Caspase-4, -2, -9[2].

Application

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Product Information

• Catalog No.: HY-B1193S
• CAS No.: 192584-82-0
• Molecular Formula: C32H38D3NO2
• Molecular Weight: 474.69
• Purity: 99.98%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source