Trimipramine maleate

Overview

Trimipramine maleate is a 5-HT receptor antagonist, with blood-brain barrier permeability. Trimipramine maleate has pK i binding values of 6.39, 8.10, 4.66 for 5-HT 1C , 5-HT 2 and 5-HT 1A , respectively. Trimipramine maleate is also a potent and selective inhibitor targeting human noradrenaline ( hNAT ), serotonin ( hSERT ) and organic cation transporters ( hOCT1 , hOCT2 ) with IC 50 values of 4.99 μM, 2.11 μM, 3.72 μM, 8.00 μM, respectively. Trimipramine maleate has vascular activity and anxiolytic efficacy.

Application

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Product Information

• Catalog No.: HY-B1213
• CAS No.: 521-78-8
• Molecular Formula: C24H30N2O4
• Molecular Weight: 410.51
• Purity: 99.88%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (6.09 mM); Clear solution
• Availability: In-stock

Source

Original product source