Flufenamic acid

Overview

Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase ( COX ), activates AMPK , and also modulates ion channels, blocking chloride channels and L-type Ca 2+ channels , modulating non-selective cation channels ( NSC ), activating K + channels . Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Musculoskeletal and Skin Disease | Products > Disease Areas > Coronavirus Infection | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Arthritis | Products > Disease Areas > Pancreatic Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Parasitic Infection | Products > Disease Areas > SARS-CoV-2 Infection | Products > Disease Areas > Vibrio Cholerae Infection | Products > Disease Areas > Hypertension | Products > Disease Areas > Rheumatoid Arthritis | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Potassium Channel | Products > Signaling Pathways > Chloride Channel | Products > Signaling Pathways > Calcium Channel | Products > Signaling Pathways > Parasite | Products > Signaling Pathways > COX | Products > Signaling Pathways > AMPK

Product Information

• Catalog No.: HY-B1221
• CAS No.: 530-78-9
• Molecular Formula: C14H10F3NO2
• Molecular Weight: 281.23
• Purity: 99.98%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 1 year , -20°C, 6 months
• Solubility: ≥ 2.5 mg/mL (8.89 mM); Clear solution
• Availability: In-stock

Source

Original product source