Trihexyphenidyl hydrochloride

Overview

Trihexyphenidyl hydrochloride is a selective and orally active M 1 muscarinic receptor antagonist with an IC 50 of 3.7 nM for rat cerebral cortex M1 muscarinic receptors. Trihexyphenidyl hydrochloride modulates cholinergic activity, countering acetylcholine supersensitivity in neural pathways. Trihexyphenidyl hydrochloride improves movement disorder, inhibits McN-A-343 ( HY-107648 )-induced pressor responses, vagally-induced bradycardia and vasodilatation. Trihexyphenidyl hydrochloride can be used for the research of Parkinson's disease..

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > mAChR | Products > Signaling Pathways > Cholinesterase (ChE)

Product Information

• Catalog No.: HY-B1277
• CAS No.: 52-49-3
• Molecular Formula: C20H32ClNO
• Molecular Weight: 337.93
• Purity: 99.44%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: 1 mg/mL (2.96 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source