Proadifen hydrochloride (Standard)

Overview

Proadifen (hydrochloride) (Standard) is the analytical standard of Proadifen (hydrochloride). This product is intended for research and analytical applications. Proadifen (SKF-525A) hydrochloride is a non-competitive Cytochrome P450 inhibitor with an IC50 value of 19 μM. Proadifen hydrochloride reduces monoamine oxidase A ( MAO-A ) activity and reverses the antidepressantlike behavioral effect of Imipramine ( HY-B1490A ) and Desipramine ( HY-B1272A ) in rats. Proadifen hydrochloride also reduces N, N-dimethyltryptamine (DMT) metabolism in liver microsomes and inhibits N-demethylationand Acridone ( HY-W007771 ) formation. Proadifen hydrochloride augments Lipopolysaccharide (LPS) ( HY-D1056 )-induced fever and exacerbates Prostaglandin E2 (PGE2) ( HY-101952 ) levels in the rat. Proadifen hydrochloride is promising for research of metabolism-related deseases, ovarian carcinoma, inflammation and dopamine neurons-related deseases[4].

Application

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Product Information

• Catalog No.: HY-B1311R
• CAS No.: 62-68-0
• Molecular Formula: C23H32ClNO2
• Molecular Weight: 389.96
• Purity: 98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source