Spiperone hydrochloride

Overview

Spiperone hydrochloride (Spiroperidol hydrochloride) is a selective dopamine D 2 receptor ( K i values of 0.06 nM, 0.6 nM, 0.08 nM, ~350 nM, ~3500 nM for D 2 , D 3 , D 4 , D 1 and D 5 receptors, respectively) and 5-HT 2A /5-HT 1A receptor ( K i s of 1 nM/49 nM) antagonist. Spiperone hydrochloride is also a selective α1B-adrenoceptor antagonist. Spiperone hydrochloride activates calcium-activated chloride channel (CaCC) . Antipsychotic and anti-inflammatory activities.

Application

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Product Information

• Catalog No.: HY-B1371A
• CAS No.: 2022-29-9
• Molecular Formula: C23H27ClFN3O2
• Molecular Weight: 431.93
• Purity: 99.0%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.08 mg/mL (4.82 mM); Clear solution
• Availability: In-stock

Source

Original product source