JP1302 is a potent, selective, high affinity antagonist of the α 2C -adrenoceptor , with a K b of 16 nM and a K i of 28 nM for the human α 2C -receptor. JP1302 shows antidepressant and antipsychotic-like effects. JP1302 can be used for neuropsychiatric disorders and renal dysfunction research.
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