Mesoridazine (TPS-23) , a metabolite of Thioridazine ( HY-B0965A ), acts as an orally active phenothiazine antipsychotic agent . Mesoridazine is a potent and rapid open-channel blocker of human ether-a-go-go related gene (hERG) channels and blocks hERG currents with an IC 50 of 550 nM (at 0 mV) in human embryonic kidney 293 cells.Mesoridazine can be used for the research of schizophrenia, as well as certain other psychiatric disorders.
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