Alovudine (3'-Fluoro-3'-deoxythymidine) is a mtDNA synthesis inhibitor and a marker of DNA synthesis. Alovudine is less susceptible to inflammatory changes than 18 F-Fluorodeoxyglucose (FDG) and thus is a better biomarker in pancreatic cancer . Alovudine shows anti-orthopoxvirus and anti-leukemic activity.
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