Benzamil

Overview

Benzamil (Benzylamiloride), an Amiloride analogue, is a Na + /Ca 2+ exchanger (NCX) inhibitor ( IC 50 ~100 nM). Benzamil also is a non-selective Deg/epithelial sodium channels (ENaC) blocker, and can potentiate myogenic vasoconstriction. Benzamil inhibits TRPP3-mediated Ca 2+ -activated currents, with an IC 50 of 1.1 μM.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Na+/Ca2+ Exchanger | Products > Signaling Pathways > Sodium Channel

Product Information

• Catalog No.: HY-B1546
• CAS No.: 2898-76-2
• Molecular Formula: C13H14ClN7O
• Molecular Weight: 319.75
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source