Frovatriptan succinate ((R)-Frovatriptan succinate) is a potent, high affinity, selective and orally active 5-HT 1B ( pK 50 of 8.2) and 5-HT 1D receptor agonist. Frovatriptan succinate exhibits >10-fold selectivity for 5-HT 1B and 5-HT 1D over 5-HT 1A , 5-HT 1F , and 5-HT 7 and >1000-fold selectivity over other 5-HT, dopamine, histamine H 1 , and α1-adrenoceptor. Frovatriptan succinate has the potential for migraine research.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > 5-HT Receptor
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