Pretilachlor

Overview

Pretilachlor is a chloroacetamide herbicide with biological activities including endocrine disruption, oxidative stress induction, apoptosis induction, and immunotoxicity. Pretilachlor exerts its effects by interfering with hormone metabolism, inducing oxidative stress, activating apoptotic pathways, and inhibiting immune functions. Pretilachlor upregulates the transcription of P53 , Mdm2 , and Bbc3 , and increases the activities of Caspase3 and Caspase9 ; it upregulates the transcription of genes in the HPG/HPT axis and the activity of aromatase ; it induces oxidative stress, elevates ROS levels, and upregulates CAT, SOD , and GPX. Pretilachlor downregulates the transcription of CXCL-C1C , IL-1β , and IL-8 . Pretilachlor disrupts the normal physiological processes and embryonic development of fish, exhibiting significant toxicity. Pretilachlor can be used in studies related to weeding, environmental pollution, and behavioral toxicity in fish.

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Research Areas > Others | Products > Signaling Pathways > Cytochrome P450 | Products > Signaling Pathways > MDM-2/p53 | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Herbicide | Products > Signaling Pathways > Environmental Pollutants | Products > Signaling Pathways > Caspase

Product Information

• Catalog No.: HY-B2035
• CAS No.: 51218-49-6
• Molecular Formula: C17H26ClNO2
• Molecular Weight: 311.85
• Purity: 99.25%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Availability: In-stock

Source

Original product source