Regorafenib

Overview

Regorafenib (BAY 73-4506) is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC 50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3 , PDGFRβ , Kit , RET and Raf-1 , respectively. Regorafenib shows very robust antitumor and antiangiogenic activity.

Application

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Product Information

• Catalog No.: HY-10331
• CAS No.: 755037-03-7
• Molecular Formula: C21H15ClF4N4O3
• Molecular Weight: 482.82
• Purity: 99.97%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 7.5 mg/mL (15.53 mM); Clear solution
• Availability: In-stock

Source

Original product source