Incadronate disodium

Overview

Incadronate disodium (YM 175) is a bisphosphonate with strong inhibitory activity on bone resorption. Incadronate disodium indirectly stimulates renal 25-hydroxyvitamin D-1-hydroxylase by increasing circulating parathyroid hormone. Incadronate disodium, a cholesterol-lowering agent, is a potent inhibitor of rat liver microsomal squalene synthase (K i =57 nM). Incadronate disodium inhibits sterol biosynthesis in mouse macrophage J774 cells (IC 50 =64 μM). Incadronate disodium has the potential for malignant tumors research.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Farnesyl Transferase

Product Information

• Catalog No.: HY-B2097
• CAS No.: 138330-18-4
• Molecular Formula: C8H17NNa2O6P2
• Molecular Weight: 331.15
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source