Regorafenib (Standard)

Overview

Regorafenib (Standard) is the analytical standard of Regorafenib. This product is intended for research and analytical applications. Regorafenib (BAY 73-4506) is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC 50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3 , PDGFRβ , Kit , RET and Raf-1 , respectively. Regorafenib shows very robust antitumor and antiangiogenic activity.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Others | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Raf | Products > Signaling Pathways > RET | Products > Signaling Pathways > c-Kit | Products > Signaling Pathways > FGFR | Products > Signaling Pathways > Tie | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > VEGFR | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > PDGFR

Product Information

• Catalog No.: HY-10331R
• CAS No.: 755037-03-7
• Molecular Formula: C21H15ClF4N4O3
• Molecular Weight: 482.82
• Purity: 98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source