ATP (Standard)

Overview

ATP (Standard) is the analytical standard of ATP. This product is intended for research and analytical applications. ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. In Vitro: ATP (5 mM; 1 hour) co-treatment with LPS (1 μg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs. ATP (2 mM; 0.5-24 hours) induces secretion of IL-1β, KC and MIP-2 from BMDMs in a caspase-1 activation-dependent manner. ATP promotes neutrophil chemotaxis in vitro. In Vivo: ATP (50 mg/kg; i.p.) protects mice against bacterial infection in vivo. ATP induces the secretion of IL-1β, KC and MIP-2 and neutrophils recruitment in vivo.

Application

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Product Information

• Catalog No.: HY-B2176R
• CAS No.: 56-65-5
• Molecular Formula: C10H16N5O13P3
• Molecular Weight: 507.18
• Purity: 95.70%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source